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pentobarbital will decrease the extent or result of elbasvir/grazoprevir by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. The therapeutic impact of elbasvir/grazoprevir might be lowered if coadministered with sturdy CYP3A inducers and is therefore contraindicated.pentobarbital will lower the extent or effect of ziprasido